Infernal - inference of RNA secondary structure alignments http://eddylab.org/infernal/ Version 1.1.3; Nov 2019 Copyright (C) 2019 Howard Hughes Medical Institute. ------------------------------------------------------------------ Infernal is an implementation of covariance models (CMs), which are statistical models of RNA secondary structure and sequence consensus. You give Infernal a multiple sequence alignment of a conserved structural RNA family, annotated with the consensus secondary structure. The "cmbuild" program builds a statistical profile of your alignment. That CM can be used as a query in a database search to find more homologs of your RNAs (the "cmsearch" program). You can also use a CM of a representative alignment of your sequence family to create a larger consensus alignment of any number of RNAs (the "cmalign" program). Infernal is the software engine underlying the Rfam RNA database (http://rfam.xfam.org/). Other files to read in the top-level source directory: INSTALL Brief installation instructions. Userguide.pdf The Infernal User's Guide. LICENSE copyright and license information To get started after installation, see the Tutorial section in the Infernal User's Guide (Userguide.pdf). ------------------------------------------------------------------- The Infernal development team github.com/EddyRivasLab/infernal/ http://eddylab.org/infernal